how would the peptide bond work with proline and other amino acids? I know when drawing other amino acid residues the formation of the peptide bond gives off h2o. Leaving a bond of c-nh-c in its place. would the bond that forms from a carboxyl end of another acid with the proline (which is short a H) be drawn c-n-c?? Sorry if this doesn't make sense, I have to draw tripeptides for a midterm and was caught up with the proline residues in a structure... let's hope the prof doesn't put that! thanks for any help!
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when a proline is present, it can form a bond either in cis or trans conformation,
in cis conformation the peptide bond can bring about a 'U' turn in the peptide chain while a trans may not
the following link may help you understand how a proline can be present in a peptide chain
http://www.google.co.in/imgres?q=peptide…
or the diagram under cyclic peptides side heading in
http://www2.chemistry.msu.edu/faculty/re…
in cis conformation the peptide bond can bring about a 'U' turn in the peptide chain while a trans may not
the following link may help you understand how a proline can be present in a peptide chain
http://www.google.co.in/imgres?q=peptide…
or the diagram under cyclic peptides side heading in
http://www2.chemistry.msu.edu/faculty/re…