Calculating frequencies m/c full points for answer + explanation please
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Calculating frequencies m/c full points for answer + explanation please

[From: ] [author: ] [Date: 13-01-21] [Hit: ]
frequency of e allele=0.2 d)frequency of E allele=0.85, frequency of e allele=0.15 e)frequency of E allele=0.9,......
I am interested in determining whether a local population of fruit flies (Drosophila melanogaster) is at Hardy-Weinberg equilibrium, so I recently visited a local orchard where I collected 100 individual flies, and took them back to the lab. There, I sequenced the DNA of each fly to determine their specific genotype at the autosomal gene locus that codes for alcohol dehydrogenase (ADH; an enzyme that is necessary for flies to metabolize and detoxify ethanol).

The results of this study revealed that there were 75 individuals that were homozygous for the dominant allele E, 10 individuals that were heterozygous, and 15 individuals that were homozygous for the recessive allele e (and are thus incapable of metabolizing and detoxifying ethanol).

What is the allele frequency of E and e in this sample
a)frequency of E allele=0.75, frequency of e allele=0.25


b)It is impossible to answer this question with the information provided.


c)frequency of E allele =0.8, frequency of e allele=0.2


d)frequency of E allele=0.85, frequency of e allele=0.15


e)frequency of E allele=0.9, frequency of e allele=0.1

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I'm afraid the answer is none of the above, because it is impossible to have a population in Hardy-Weinberg equilibrium in which the hybrids number less than either the homozygous recessive or homozygous dominant. Therefore, there was probably a sampling error (or your teacher was making up numbers).

The background: You have 2 of each kind of chromosome, one inherited from your mother, one from your father. Both the chromosomes have the same genes. For example, if the gene is for eye color, there is one of that kind of gene on each of the chromosomes (regardless of what information is actually there). Let's say there are two alleles, one for brown eyes, which is dominant B, on one for blue eyes, which is recessive b. (let's keep it simple and say those are the only two possibilities, even though it's not like that in real life - there are actually multiple genes that influence eye color, which is why you could actually have gray or hazel colored eyes).
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