Best one in general? H2O, H3CO-, OH-, H2N-, H3COH
Best for an SN2 reaction with 1-Chlorodecane? CH3CH2OH, CH3COO-, OH-, CH3CH2O-, H2O, (CH3)3CO-
I do know that H2O is a really bad nucleophile, but not sure why, and I'm completely clueless about the rest.
Best for an SN2 reaction with 1-Chlorodecane? CH3CH2OH, CH3COO-, OH-, CH3CH2O-, H2O, (CH3)3CO-
I do know that H2O is a really bad nucleophile, but not sure why, and I'm completely clueless about the rest.
-
I'm not certain which is the best nucleophile in general. I think it is -NH2 because it is less electronegative and is ready to give up its charge. Nucleophiles are electron pair donors.
For 1-chlordecane, -OH is the best for an SN2 reaction (this is best at room temperature because in the presence of heat and elimination reaction will occur).
H2O is a bad nucleophile because upon attack of the substrate, the oxygen will form a positive charge and will either leave the molecule or require a base to remove a proton from the cation.
I hope I was able to help.
For 1-chlordecane, -OH is the best for an SN2 reaction (this is best at room temperature because in the presence of heat and elimination reaction will occur).
H2O is a bad nucleophile because upon attack of the substrate, the oxygen will form a positive charge and will either leave the molecule or require a base to remove a proton from the cation.
I hope I was able to help.