Do any compounds in ackee have any potential in medicine
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Do any compounds in ackee have any potential in medicine

[From: ] [author: ] [Date: 11-09-05] [Hit: ]
ophthalmic conjunctivitis (eye inflammation) and headache. More research is needed to make a recommendation of the therapeutic benefits of ackee. Due to its toxicity, the importation of this fruit into the USA is forbidden by the U.S. Food and Drug Administration.......
The ackee is a major food in Jamaica. In South America, the fruit has been used to treat colds, fever, and diseases as varied as edema and epilepsy, although there are no clinical trials to support these uses. The ripe fruits are edible, however, the unripe fruits are toxic due to hypoglycins A and B. Because ackee has no data supporting a medicinal use, all adverse reactions are addressed under Toxicology.
http://www.drugs.com/npp/ackee.html

Various parts of the ackee tree have been used medicinally to expel parasites and to treat dysentery (severe diarrhea), ophthalmic conjunctivitis (eye inflammation) and headache. More research is needed to make a recommendation of the therapeutic benefits of ackee. Due to its toxicity, the importation of this fruit into the USA is forbidden by the U.S. Food and Drug Administration.
http://www.healthline.com/natstandardcon…

Traditional medicinal uses of ackee

In total, 22 diseases have been recognized to be healed with ackee. Dental decay, fever, malaria, internal haemorrhage, dysentery, burns, eyes inflammation, yellow fever, constipation, cutaneous infections, whitlow and head lice are the most common. All parts (bark, capsules, seeds, roots, leaves) are involved in the composition of drugs (Table 5). The bark is useful in the treatment of 13 different diseases followed in decreasing order by leaves (8), capsules (3), roots and seeds (2). This type of knowledge is kept mostly by old people and traditional healers in the communities and varied sometimes from one ethnic group to the other.

Some of the medicinal values attributed to ackee in Benin are known in other countries where the species occurs as well. The bark is used in Ivory Coast together with some spices to relieve pains; leaves and barks are used in association to treat sore stomach, epilepsy and yellow fever in Columbia. In Ghana, the bark is one of the ingredients used in a concoction administered for epilepsy; leave juice is used for washing or as drops for sore eyes, conjunctivitis and trachoma; the pulp of twiggy leaves is applied on the forehead to treat migraine/headache. B. sapida is also a natural source of carboxycyclopropylglycine used in pharmacy. The extraction of this non-proteinogenic amino acid from ackee offers the possibility of avoiding the expensive synthetic procedures. Furthermore, B. sapida has antidiabetic activity. The use of this important traditional medicinal knowledge in a rational way remains a challenge to modern scientific disciplines such as pharmacology. More research is necessary to analyze the properties and therapeutic virtues attributed to the soap as a preliminary step to the mechanization of the production. The confirmation of the virtues of ackee soap can boost its production and contribute to a better valorisation of the enormous quantity of capsules and seeds that are usually thrown away.

Ackee is not well known in Benin for its utility as repellent. However, experiments conducted in Trinidad and Tobago had shown that other fruit parts (epidermis, aril and seed) have repellent properties against stored-product insect pests, namely, Callosobruchus maculatus, Cryptolestes ferrugineus, Tribolium castaneum and Sitophilus zeamais
http://www.ethnobiomed.com/content/6/1/1…
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