Gene expression is often assayed by measuring the level of mRNA produced from a gene. If one is interested in knowing the amount of a final active gene product, a potential problem of this method is that it ignores the possibility of _____.
a. chromatin condensation control
b.translational control
c.alternative splicing
d.transcriptional control
a. chromatin condensation control
b.translational control
c.alternative splicing
d.transcriptional control
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b.translational control
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Answer would be B. Translational Control.
If one is interested in knowing the amount of a final active gene product, one should estimate or measure the amount of the active protein after the mRNA is TRANSLATED. Problem with measuring the level of mRNA produced from a gene is that not all mRNAs are translated, some are silenced by siRNA, etc. Therefore the limiting element here will be the ribosomes, transcription factors, etc that are responsible for translation.
If one is interested in knowing the amount of a final active gene product, one should estimate or measure the amount of the active protein after the mRNA is TRANSLATED. Problem with measuring the level of mRNA produced from a gene is that not all mRNAs are translated, some are silenced by siRNA, etc. Therefore the limiting element here will be the ribosomes, transcription factors, etc that are responsible for translation.