What mechanism do eukaryotic cells employ to keep their chromosomes from replicating more than once per cell cycle?
And could you put the answer in simple terms so I can really understand it
I have no idea what the answer could be. Any help would be greatly appreciated
Please and Thank You :)
And could you put the answer in simple terms so I can really understand it
I have no idea what the answer could be. Any help would be greatly appreciated
Please and Thank You :)
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http://en.wikipedia.org/wiki/Eukaryotic_…
It lists the reasons the chromosomes can't reproduce more than once per cycle. There is a protein called Geminin, DNA replication inhibitor that builds in concentration eventually binding to Cdt1 (used in a chromosome replication phase) and sequesters it. Additionally, a phosphate compound gets added to Cdc6/18 (used in another chromosome replication phase) thus preventing it from binding to the ORC and is a second reason the further copying of chromosomes is not possible.
It lists the reasons the chromosomes can't reproduce more than once per cycle. There is a protein called Geminin, DNA replication inhibitor that builds in concentration eventually binding to Cdt1 (used in a chromosome replication phase) and sequesters it. Additionally, a phosphate compound gets added to Cdc6/18 (used in another chromosome replication phase) thus preventing it from binding to the ORC and is a second reason the further copying of chromosomes is not possible.