my doctor prescribed 200 mgs of ketamine in a nasal spray to try and treat my depression, and so far all it it does is make me sleepy. but i have been reading all over the internet how "low dose ketamine" can help depression. doses as low as 25mgs. could this betbetter for me? and could it be better if it is injected rather than taken in a nasal spray?
i just feel kind of weird about the nasal spray since it feels like half of it drains down to the back of my tongue after i spray it.
dont worry, i dont plan on changing how i take it unless my psychiatrist approves it that way.
i just feel kind of weird about the nasal spray since it feels like half of it drains down to the back of my tongue after i spray it.
dont worry, i dont plan on changing how i take it unless my psychiatrist approves it that way.
-
It sounds like the absorption rate of using an inhaler @ 200mg far exceeds the prescribed
amounts that are attributed to published research studies. You are basically overdosing on the ketamine. Inhalation exceeds intravenous absorption rates. With inhalation it is the fastest method, 7–10 seconds for the drug to reach the brain. And, there is no way to control the amount of medicine that is absorbed.
With intravenous administration it takes 15–30 seconds for IV, 3–5 minutes for IM and subcutaneous (subcut).
January 2010 edition of "Addiction," found that people who used ketamine at least four times a week for a year had problems with memory, verbal fluency, delusions, depression, dissociation and psychosis. However, these subjects took ketamine at far higher doses than used in the antidepressant studies. It does have implications as to whether repeated administration similar to that in the study by Price would have long-term effects. Further studies are being carried out on this matter with both ketamine and other similar acting drugs.
Human clinical trials of ketamine as a rapidly acting antidepressant aren't especially new. A randomized, double-blind study in 2000 involved administration of saline or a single subanesthetic dose of ketamine (0.5 mg/kg intraveneously) to nine depressed patients, seven of whom completed the trial (Berman et al., 2000).
amounts that are attributed to published research studies. You are basically overdosing on the ketamine. Inhalation exceeds intravenous absorption rates. With inhalation it is the fastest method, 7–10 seconds for the drug to reach the brain. And, there is no way to control the amount of medicine that is absorbed.
With intravenous administration it takes 15–30 seconds for IV, 3–5 minutes for IM and subcutaneous (subcut).
January 2010 edition of "Addiction," found that people who used ketamine at least four times a week for a year had problems with memory, verbal fluency, delusions, depression, dissociation and psychosis. However, these subjects took ketamine at far higher doses than used in the antidepressant studies. It does have implications as to whether repeated administration similar to that in the study by Price would have long-term effects. Further studies are being carried out on this matter with both ketamine and other similar acting drugs.
Human clinical trials of ketamine as a rapidly acting antidepressant aren't especially new. A randomized, double-blind study in 2000 involved administration of saline or a single subanesthetic dose of ketamine (0.5 mg/kg intraveneously) to nine depressed patients, seven of whom completed the trial (Berman et al., 2000).
12
keywords: of,Can,effect,from,dose,intranasal,have,different,injecting,low,ketamine,Can injecting a low dose of ketamine have a different effect from intranasal ketamine